Effect of Adding Sildenafil to Clomiphene Citrate Versus Clomiphene Citrate Alone on Endometrial Receptivity in un Ovulatory PCO Patients
نویسندگان
چکیده
منابع مشابه
Effect of Adding Sildenafil to Clomiphene Citrate versus Clomiphene Citrate alone on Endometrium in Unexplained Infertility: Cross-Sectional, Non-Randomized Study
to a receptive endometrium suitable for implantation. One of the major drugs used for infertility treatment is clomiphene citrate (a non steroidal synthetic compound with both estrogenic and anti-estrogenic activity). Clomiphene citrate stimulates ovulation by competitively inhibiting the estrogen (E) binding to the hypothalamic estrogen receptors (ER), thereby releasing the hypothalamus from t...
متن کاملAdding sildenafil vaginal gel to clomiphene citrate in infertile women with prior clomiphene citrate failure due to thin endometrium: a prospective self-controlled clinical trial
We aimed to investigate the effect of adding sildenafil vaginal gel to clomiphene citrate (CC) in infertile women with prior CC failure. METHODS This is a self- controlled clinical trial. Women with CC failure (in prior 5 cycles) and thin endometrium were recruited (N = 42). In their 6th (CC only) cycle, women continued on CC 100 mg/ day for 5 days, and had measurement of endometrial thicknes...
متن کاملLetrozole versus Clomiphene Citrate in Patients with Anovulatory Infertility
Objective: To compare the effectiveness of letrozole and clomiphene citrate (CC) in patients with anovulatory infertility. Design: Open, prospective, randomized, parallel group, multicentric, comparative trial. Setting: Outpatient clinics of infertility centers in India. Patient(s): Fifty-five patients with anovulatory infertility were recruited. Twenty-seven patients (59 cycles) were given let...
متن کاملEfficacy of combined metformin–clomiphene citrate in comparison with clomiphene citrate alone in infertile women with polycystic ovarian syndrome (PCOS)
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women and is associated with the reproductive and metabolic disorders. OBJECTIVES To compare the ovulation and conception rates after the treatment with Clomiphene Citrate (CC) alone and in combination with metformin in infertile patients presented with polycystic ovarian syndrome (PCOS). MATERIAL & METHODS Thi...
متن کاملP-199: Comparison of Clomiphene Citrate and Letrozole Effect on Folliculogenesis in Polycystic Ovarian Syndrome Patients
Background: Polycystic ovarian syndrome (PCOS) which is the most common form of anovulatory infertility affects 5-10% women of reproductive age. Clomiphene Citrate (C.C) is the first line treatment in infertile women entering intrauterine insemination (IUI) cycle. For C.C resistant patients the second approach is aromatase inhibitors such as Letrozole. The aim of this study is to compare the ef...
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ژورنال
عنوان ژورنال: Benha Journal of Applied Sciences
سال: 2021
ISSN: 2356-976X
DOI: 10.21608/bjas.2020.135859